The Myc Gene: Methods and Protocols (Methods in Molecular Biology #2318) (Hardcover)

The Myc Gene: Methods and Protocols (Methods in Molecular Biology #2318) By Laura Soucek (Editor), Jonathan Whitfield (Editor) Cover Image
By Laura Soucek (Editor), Jonathan Whitfield (Editor)
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Description


1. An "-omycs" Toolbox to Work with MYC

Jonathan R. Whitfieldand Laura Soucek

2. Methods of Expression, Purification and Preparation of the c-Myc b-HLH-LZ for its Biophysical Characterization Patrick Delattre, Martin Montagne, and Pierre Lavigne

3. Biophysical and Structural Methods to Study the bHLHzip Region of Human c-MYC

Giovanna Zinzalla

4. Identifying and Validating MYC: protein Interactors in Pursuit of Novel anti-MYC Therapies

Diana Resetca, Alannah S. MacDonald, Tristan M. G. Kenney, Yong Wei, Cheryl H. Arrowsmith, Brian Raught, and Linda Z. Penn

5. Detection of Post-Translational Modifications on MYC

Colin J. Daniel, Xiao-Xin Sun, Yingxiao Chen, Xiaoli Zhang, Mu-Shui Dai, and Rosalie C. Sears

6. MYC Analysis in Cancer and Evolution

Markus Hartl and Klaus Bister

7. Genome-wide analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA-binding by Next Generation Sequencing

Rene Jackstadt, Markus Kaller, Antje Menssen, and Heiko Hermeking

8. Analysis of Myc Chromatin Binding by Calibrated ChIP-seq Approach

Donald P. Cameron, Vladislav Kuzin, and Laura Baranello

9. A High-Throughput Chromatin Immunoprecipitation Sequencing Approach to Study the Role of MYC on the Epigenetic Landscape

Luca Fagnocchiand Alessio Zippo

10. Methods for Determining Myc-induced Apoptosis

Dan Lu, Catherine Wilson, and Trevor D. Littlewood

11. Measuring MYC-mediated Metabolism in Tumorigenesis

Hsin-Yao Tang, Aaron R. Goldman, Xue Zhang, David W. Speicher, and Chi V. Dang

12. Methods to study Myc-regulated Cellular Senescence - An Update

Fan Zhang, Wesam Bazzar, Mohammad Alzrigat, and Lars-Gunnar Larsson

13. Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer

Joanna R. Kovalski, Yichen Xu, and Davide Ruggero

14. A Versatile in vivo System to Study Myc in Cell Reprogramming

Elena Senis, Lluc Mosteiro, Dirk Grimm, and Maria Abad

15. Using Flow Cytometry to Study Myc's Role in Shaping the Tumor Immune Microenvironment

S lvia Casacuberta-Serra

16. Generation of a Tetracycline Regulated Mouse Model of MYC-Induced

T-Cell Acute Lymphoblastic Leukemia

Wadie D. Mahauad-Fernandez, Kavya Rakhra, and Dean W. Felsher

17. Chromogenic in Situ Hybridization (CISH) as a Method for Detection of C-Myc Amplification in Formalin-Fixed Paraffin-Embedded Tumor Tissue: An Update

Natasa Todorovic-Rakovic

18. MYC Copy Number Detection in Clinical Samples using a Digital DNA-Hybridization and Detection Method

Zighereda Ogbah, Francesco Mattia Mancuso, and Ana Vivancos

19. Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules

Catherine A. Burkhart, Michelle Haber, Murray D. Norris, Andrei V. Gudkov, and Mikhail A. Nikiforov

Product Details
ISBN: 9781071614754
ISBN-10: 1071614754
Publisher: Humana
Publication Date: June 22nd, 2021
Pages: 349
Language: English
Series: Methods in Molecular Biology